Stories about the people, science and research of the Medical Research Council.
17 Jan 2019
Many of us enjoy raising a glass when we celebrate, socialise or relax after work. But do you know, or even think, about what’s inside? According to Senior Research Associate Dr Anna Blackwell, probably not. Now that alcohol misuse is the biggest risk factor for ill health, disability and early death for 15 to 49-year-olds in England, Anna tells us why this needs to change.
There are carefully crafted cues all around you that influence your behaviour. Many of these come from industry, like the two-for-one deals or pretty bottles that make you more likely to choose one drink over another. Or the nice sofas and cosy atmosphere that might encourage you to stay longer in a bar then you’d planned. [...]
Continue reading: How can we help drinkers make healthier choices?
9 Jan 2019
This festive season, stem cell scientist Professor Bobby Gaspar, from the UCL Great Ormond Street Institute of Child Health, appeared as a special guest on the BBC Royal Institution Christmas Lectures. Here he shares the thrill of healing patients using gene therapy – and why it’s so important to communicate the science behind new medicines to the world.
Professor Aoife McLysaght, gene therapy patient Rhys & Professor Bobby Gaspar. Image: Paul Wilkinson Photography
To be a part of the Christmas Lectures alongside Rhys, the first patient to be successfully treated at Great Ormond Street Hospital with gene therapy back in 2001, was very special. [...]
Continue reading: Sharing the science of gene therapy
20 Dec 2018
Image credit: NordWood Themes
As we’re counting down the days ‘til Christmas, Petra Kiviniemi takes us on an MRC-countdown through our top 10 most-read blog posts of the year.
Continue reading: Our top 10 blog posts of 2018
11 Dec 2018
In India, more than 75% of people experiencing mental illness have no access to mental healthcare. Working with the Sangath organisation in Goa, Research Assistant Alison Garber explains how she’s hoping to provide healthcare from a distance for people in rural communities.
Meet Priya*, a 25-year-old woman who lives in a remote village in Goa, India. Ever since her adolescence, she’s been experiencing severe mental health issues that deeply affect her family. She breaks objects at home and hurts herself by hitting her hands and legs repeatedly. The family have travelled great distances seeking help, but with no success. They are growing increasingly desperate. [...]
Continue reading: Connecting urban psychiatry with rural India
7 Dec 2018
A team in Edinburgh is conducting vital research into how to improve the lives of more than 170 million women globally affected by endometriosis, a debilitating condition that often goes undiagnosed. Here, project co-director and principal investigator at the MRC Centre for Reproductive Health, Professor Andrew Horne, explains how a £100,000 donation from the Charles Wolfson Charitable Trust will support their vital research into the condition.
While 80 per cent of adults are familiar with diabetes, fewer than 20 per cent have heard of endometriosis. That startling figure, provided by Endometriosis.org, emphasises one of the reasons why it is such a difficult condition to research, and why developing better management and treatment remains a challenge.
Andrew Horne and his research team are conducting vital research into endometriosis, part funded by a
£100,000 donation from the Charles Wolfson Charitable Trust [...]
Continue reading: Hidden suffering
28 Nov 2018
Fraser Shearer, MRC PhD student at the Centre for Cardiovascular Science, The University of Edinburgh was commended in this year’s Max Perutz Science Writing Award. He describes how understanding the impact of stress hormones during pregnancy on a child’s lifelong mental health, could help us treat poor mental health more effectively in future.
In just a few weeks my first child is due. I have unbuilt furniture sitting in a wholly unprepared ‘nursery’ which is also my partner’s office, a pram that I am still unsure about, sleep sacks that are apparently a thing babies use and, for someone who does not have breasts, I have a wealth of knowledge about breast pumps. This, however, pales in comparison to the list of things I do not have and the window for fulfilling that list is rapidly shrinking. Suffice it to say, my stress hormone levels are elevated. [...]
Continue reading: Keep calm and carry to term
20 Nov 2018
Our runner-up in this year’s Max Perutz Science Writing Award was Briet Bjarkadottir, an MRC PhD student at the University of Oxford. By understanding how chemotherapy drugs can cause infertility she’s hoping to find a less invasive way to protect fertility in girls and women with a cancer diagnosis.
Briet Bjarkadottir & Fiona Watt
Jane is experiencing the worst day of her life. Her six-year-old daughter, Lily, has just been diagnosed with cancer. The doctor is describing the treatment plan for the next few months: several rounds of chemotherapy to hopefully kill off the cancer cells. He even mentions the possibility of a bone marrow transfer. All of this is way too much to take in – how can a little girl, who was happily playing on holiday a few weeks ago, be so sick? [...]
Continue reading: Stopping the conveyor belt – cancer and fertility
12 Nov 2018
From the Atlantic Ocean to our own backyards, our researchers have been hunting high and low for inspiration to help better understand and tackle superbugs. For World Antibiotic Awareness Week Jonathan Pearce, MRC’s Head of Infections and Immunity, highlights some of the remarkable interdisciplinary teams carrying out this fascinating research.
Today, more than ever, we’re aware of antibiotic resistance as a growing, global problem that desperately needs an answer. According to recent reports, by 2050 superbugs could kill more people than cancer and diabetes combined.
Petri dishes showing bacteria cultures.
Over the past five years alone, in partnership with the other UKRI councils, we’ve made huge efforts to better understand this threat and find solutions – together investing £44 million in 78 UK projects and £41 million in projects worldwide. Collaboration helps fire up imagination, insight and innovation. That’s why we’ve brought together researchers with different skills and experiences across the sciences, engineering, arts and humanities. [...]
Continue reading: From deep-sea sponges to dragonfly wings: Superbug research from unexpected places
8 Nov 2018
Each year the Home Office publishes figures on the number of animals used in scientific procedures in the UK. For the first time, additional statistics have today been published on all animals involved in research – a welcome milestone for animal research transparency. But what are these additional statistics? And why are some animals not counted in the statistics on procedures? Dr Sara Wells, Director of the MRC Mary Lyon Centre MRC Harwell, explains.
The biology we share with animals makes them incredibly useful for studying how our bodies work when healthy and how they change when affected by a disease. Research using animals has helped us make great progress in our understanding and treatment of disease including high blood pressure and asthma. [...]
Continue reading: Increasing transparency in animal research numbers
26 Oct 2018
Congratulations to MRC PhD student Natasha Clarke, from St George’s, University of London, winner of our 2018 Max Perutz Science Writing Award. In her award-winning article she describes how teaching machines to detect changes in language could help with early diagnosis of Alzheimer’s disease.
Award-winner Natasha (centre) with other shortlisted entrants (behind), judge Andy Ridgway
(front row left), MRC Executive Chair Professor Fiona Watt who chaired the judging panel
(front row, second from right) and Professor Robin Perutz, son of Max Perutz (front row right).
I’d like to give you a quick task. How do you make a cup of tea? Describe it out loud. Whilst this could lead to some controversies (milk in first, or last?) it seems fairly simple. But what if I told you that this task could help diagnose Alzheimer’s disease? [...]
Continue reading: How artificial intelligence, and a cup of tea, could help diagnose Alzheimer’s disease