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Insight blog: Posts tagged with MRC Mary Lyon Centre

Stories about the people, science and research of the Medical Research Council.

MRC Festival: Bringing research to life

15 Aug 2018

Are you interested in coming along or taking part in next year’s MRC Festival of Medical ResearchDeborah Barber explores some 2018 highlights and shares tips learnt along the way for making public engagement a success.

For the last three years we’ve kicked off our summer with the MRC Festival of Medical Research. This year, over 10 days in June, 43 events were held by MRC institutes, units and centres, and teams of MRC grant holders. [...]

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Remembering Mary Lyon and her impact on mouse genetics

3 Feb 2015

Dr Mary Lyon, an important figure in the field of mouse genetics, died in December. Here Katherine Nightingale looks back on her career, from a ‘titular’ degree to her impact on generations of scientists, via a discovery in the early 1960s which explained a fundamental difference between men and women in the inheritance of disease.

A portrait of Mary Lyon by artist Dr Lizzie Burns

A portrait of Mary Lyon by artist Dr Lizzie Burns (Image copyright: Dr Lizzie Burns)

It’s not often that the MRC names a building after a scientist, even with our roll-call of scientific greats. But at MRC Harwell in Oxfordshire, the MRC Mary Lyon Centre teems with life — murine life that is. Opened in 2004, the centre is a national facility for mouse genetics where genetically modified mice are produced, cared for and studied.

Mary Lyon, who died on Christmas day 2014 aged 89, worked with mice throughout her scientific career, becoming one of the foremost geneticists of the 20th century through her research on mice with mutated genes. She made her most famous discovery, named ‘lyonisation’ in her honour, during her time at MRC Harwell.   [...]

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Video: Using mice in hearing research

5 Mar 2014

How are mice helping with hearing research? Professor Steve Brown, the Director of the MRC Mammalian Genetics Unit, carries out research investigating the genetic basis of deafness by changing specific genes in mice to find out their role in hearing. His work has led to the identification of a potential new treatment for glue ear in children. Here he describes the work of the MRC Mary Lyon Centre and shows us a hearing experiment in which an anaesthetised mouse is tested for its response to a particular tone.

[Video link for access.] [...]

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