Stories about the people, science and research of the Medical Research Council.
12 Nov 2018
From the Atlantic Ocean to our own backyards, our researchers have been hunting high and low for inspiration to help better understand and tackle superbugs. For World Antibiotic Awareness Week Jonathan Pearce, MRC’s Head of Infections and Immunity, highlights some of the remarkable interdisciplinary teams carrying out this fascinating research.
Today, more than ever, we’re aware of antibiotic resistance as a growing, global problem that desperately needs an answer. According to recent reports, by 2050 superbugs could kill more people than cancer and diabetes combined.
Petri dishes showing bacteria cultures.
Over the past five years alone, in partnership with the other UKRI councils, we’ve made huge efforts to better understand this threat and find solutions – together investing £44 million in 78 UK projects and £41 million in projects worldwide. Collaboration helps fire up imagination, insight and innovation. That’s why we’ve brought together researchers with different skills and experiences across the sciences, engineering, arts and humanities. [...]
Continue reading: From deep-sea sponges to dragonfly wings: Superbug research from unexpected places
1 Aug 2018
Antimicrobial resistance (AMR) is one of the most serious global threats to human health in the 21st century. One of the researchers taking on this challenge is Professor Matthew Avison of the University of Bristol who is leading the ‘One Health Drivers of Antibacterial Resistance in Thailand’ consortium project. Here, he tells us about the benefits of working together across borders and disciplines, and how the consortium’s approach can help inform AMR research worldwide.
In Thailand, AMR is estimated to have led to 38,000 deaths in 2010 and cost the economy $1.2 billion. Since then, the problem has continued to grow.
The Thai authorities are monitoring the situation closely and the World Health Organisation recognises their surveillance as an exemplary model for other low- and middle-income countries (LMICs). But the research to date has been in discrete areas.
Ta Chin River [...]
Continue reading: Antimicrobial resistance in Thailand: taking a holistic approach
10 May 2018
Last month, our researchers channelled their creativity into a one-off UK Research and Innovation (UKRI) Superheroes vs Superbugs night at the Science Museum in London. Over 1,000 people came to meet some of the superheroes taking on the fight against the global threat of antimicrobial resistance. Petra Kiviniemi reports.
Antibiotics underpin nearly every aspect of modern medicine, but ever-increasing numbers of pathogens are becoming resistant to our arsenal of drugs. So now researchers are working harder than ever to discover new ways to prevent and treat drug-resistant infections.
Scientists transported guests into the hidden world of bacteria, using virtual reality to shrink them down to the size of bacterial proteins.
The Science Museum currently plays host to Superbugs: The Fight for our lives. It’s an exhibition for anyone to visit and learn about the causes, consequences, and possible solutions for the growing problem of antimicrobial resistance (AMR). [...]
Continue reading: Superbugs vs Superheroes: Getting creative with antimicrobial resistance
13 Nov 2017
Bacteria resistant to drugs are stopping us from treating infectious diseases and undermining medical advances. So what can we do about it? This WHO Antibiotic Awareness Week Dr Jonathan Pearce, Head of Infections and Immunity at the MRC, explains why understanding how resistance develops and spreads is key to tackling antibiotic resistance. And how using this knowledge, we can find creative new ways of preventing and treating infections.
Enterobacteria grown on a selective agar plate.
Antibiotic resistance is now recognised as one of the most serious threats to human health, spreading across national boundaries. It arises from a complex interplay between biomedical, animal, social, cultural and environmental factors. If we are to meet this challenge, we need to take both an international and interdisciplinary approach. [...]
Continue reading: Antibiotic resistance: how we’ll beat it together
17 Nov 2016
Last year a UK-China research collaboration took an unexpected turn following the discovery of resistance to the ‘last resort’ antibiotic: colistin. Here Professor Timothy Walsh, Professor of Medical Microbiology at Cardiff University, describes how the global community can learn from the positive steps taken by the Chinese Government.
Antibiotic resistance is really all about people and society. We often blame antimicrobial resistance on the bug and how resistance can travel from one bug to another. But different sectors, for example farming, hospitals and communities, are all critically linked. [...]
Continue reading: Global action on antimicrobial resistance