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Insight blog: Posts tagged with mouse genetics

Stories about the people, science and research of the Medical Research Council.

New investment in mouse research to enhance national coordination and collaboration

13 Dec 2019

Following on from previous blog posts discussing our commitment to mouse-based research and our strategic review of mouse genetics, here our Executive Chair Professor Fiona Watt sets out the MRC’s plans for a national network of mouse research excellence, with the Mary Lyon Centre positioned at its heart.

Small experimental mouse is on the researcher's hand

The MRC Council recently considered the recommendations of the MRC strategic review of mouse genetics and the role of the MRC Harwell Institute, which comprises the Mammalian Genetics Unit (MGU) and the Mary Lyon Centre (MLC). The Council concluded that future investment in mouse genetics should move away from large, hypothesis-free genome-wide programmes and focus instead on more targeted programmes that are integrated with human disease modelling. [...]

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To the Crick! Part two: The Royal Society welcomes its first collection of personal papers from a female Fellow

8 Mar 2016

In ‘To the Crick! Part 1: Moving home after 100 years’ we talked about how items like personal papers from the MRC National Institute for Medical Research (NIMR) archives are in need of a new home. The papers of one of NIMR’s most famous names, Rosa Beddington, are being rehoused in the archive of The Royal Society. Royal Society archivist Laura Outterside is celebrating the arrival of the first collection of personal papers from a female Fellow of the Royal Society (FRS). This post was originally published on The Respository and has been adapted and reproduced here with kind permission from The Royal Society.

Rosa Beddington

Rosa Beddington on admissions day in 1999 when she became a Fellow of the Royal Society. ©The Royal Society

What better way for the Royal Society archive to celebrate International Women’s Day than by welcoming our first collection of personal papers from a female Fellow? We’ve recently had the good news that the Royal Society archive will be the new home for the papers of Rosa Beddington, a developmental biologist at the NIMR who became a Fellow of the Royal Society in 1999. [...]

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Remembering Mary Lyon and her impact on mouse genetics

3 Feb 2015

Dr Mary Lyon, an important figure in the field of mouse genetics, died in December. Here Katherine Nightingale looks back on her career, from a ‘titular’ degree to her impact on generations of scientists, via a discovery in the early 1960s which explained a fundamental difference between men and women in the inheritance of disease.

A portrait of Mary Lyon by artist Dr Lizzie Burns

A portrait of Mary Lyon by artist Dr Lizzie Burns (Image copyright: Dr Lizzie Burns)

It’s not often that the MRC names a building after a scientist, even with our roll-call of scientific greats. But at MRC Harwell in Oxfordshire, the MRC Mary Lyon Centre teems with life — murine life that is. Opened in 2004, the centre is a national facility for mouse genetics where genetically modified mice are produced, cared for and studied.

Mary Lyon, who died on Christmas day 2014 aged 89, worked with mice throughout her scientific career, becoming one of the foremost geneticists of the 20th century through her research on mice with mutated genes. She made her most famous discovery, named ‘lyonisation’ in her honour, during her time at MRC Harwell.   [...]

Continue reading: Remembering Mary Lyon and her impact on mouse genetics