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Insight blog: Posts tagged with tuberculosis

Stories about the people, science and research of the Medical Research Council.

Working life: Professor Janet Darbyshire

8 Feb 2018

Professor Janet Darbyshire worked in medicine and then clinical trial based research from the early 1970s. Playing an instrumental role in the development of HIV treatment, she’s worked on and coordinated many clinical trial programmes in the UK and Africa. Last month we celebrated her achievements at a ceremony held within the Houses of Parliament, awarding Janet our most prestigious award, the MRC Millennium Medal. Here Janet tells us about her early memories of medicine, giraffes in Africa and the changes she’s seen her research make to people’s lives.

Career in brief [...]

  • Qualified in medicine at The University of Manchester in 1970
  • MSc in Epidemiology from the London School of Hygiene and Tropical Medicine 1990
  • Became head of the MRC HIV Clinical Trials Centre in London in 1989
  • In 1998 established, and became director of, the MRC Clinical Trials Unit (CTU)
  • Awarded an OBE in 1996 and a CBE in 2010 for services to clinical sciences

Continue reading: Working life: Professor Janet Darbyshire

To the Crick! Part 5: 100 years of tuberculosis research and 70,000 years of evolution

20 Dec 2016

For our final post in the ‘To the Crick’ series, we hear from Luiz Pedro Carvalho. He’s moving from the site of what was the National Institute of Medical Research (NIMR) in Mill Hill to the new Francis Crick Institute building in King’s Cross. We find out about Luiz’s work, focused on tuberculosis (TB), and look back at over 100 years of MRC-funded TB research.

a side view of open-plan lab space inside the Crick

Open-plan lab spaces inside the Crick

“It’s a mixture of excitement and already missing the place,” says Luiz. Mill Hill was home to NIMR for most of its lifetime but activities there have nearly come to an end. The venerable institute is now part of the Francis Crick Institute. [...]

Continue reading: To the Crick! Part 5: 100 years of tuberculosis research and 70,000 years of evolution

World TB Day 2016: Treating TB faster

23 Mar 2016

Researchers at the MRC Clinical Trials Unit at UCL are working on projects to tackle different forms of tuberculosis (TB) with shorter treatment programmes. The STREAM project is looking at multidrug-resistant TB, the TRUNCATE project is looking at drug sensitive TB, and the SHINE project is investigating new, shorter treatments for children with TB.   

Infograohic: TB kills three people a minute, treatment takes two years for drug resistant strains, trials will determine whether shorter treatments are as effective which could mean faster recovery and less resistance.
Tuberculosis kills three people every minute. Treatment invariably involves a long course of drugs and the burden of disease falls hardest on low-income countries with stretched health systems. Three projects are running at the MRC Clinical Trials Unit to investigate the efficacy of shorter courses of drugs in some of the countries worst affected by TB. [...]

Continue reading: World TB Day 2016: Treating TB faster