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Impact story

Stem cell-derived liver models allow scientists to develop new techniques for the potential treatment of liver disease

1 Nov 2017

Scientists at the MRC Centre for Regenerative Medicine at the University of Edinburgh have developed a new technique using stem cells to generate a liver ‘model’. Using this model, the team have focused on developing new techniques that could reduce the need for liver transplants. In 2016, microRNAs to treat drug-induced toxicity were developed, followed by stem cell implants to treat liver disease in 2018.

Impact story

Gene therapy successfully treats 'Bubble Boy disease' in children

1 Nov 2017

MRC-funded scientists at the UCL Institute of Child Health have developed a successful treatment for children with ‘Bubble boy disease’, a rare immune disorder. In 2015, this work led to the launch of Orchard Therapeutics, a spin-out company which aims to further develop gene therapy to benefit patients with serious and life-threatening diseases.

Impact story

MRC research influences NHS Diabetes Prevention Programme

1 Nov 2017

The NHS Diabetes Prevention Programme was launched in 2016, and will eventually cover 26 million people. Two researchers funded through the MRC-led National Prevention Research Initiative have been influential in contributing to this important programme, demonstrating a compelling example of prevention research being translated into healthcare to improve human lives.

Impact story

Daily pill to prevent HIV infection: the PROUD Study

1 Nov 2017

The ground-breaking results from the PROUD study, published in 2016, indicate that a treatment known as PrEP is highly protective for a high-risk group of people, reducing the risk of infection by 86 per cent. This protection is the highest reported from a randomised controlled trial of PrEP to date

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MRC scientist wins 2017 Nobel Prize in Chemistry

4 Oct 2017

The MRC Laboratory of Molecular Biology is delighted to announce the awarding of the 2017 Nobel Prize in Chemistry to Dr Richard Henderson, jointly with Professor Jacques Dubochet and Dr Joachim Fran.

Impact story

MRC-funded research influences 2015 NICE Dementia Guidelines

21 Aug 2017

The MRC Cognitive Function and Ageing Study (CFAS) has led to important insights into the association of lifestyle factors with the risk of cognitive impairment. In 2015 the findings from this important study helped predict future demand for long term care and likely associated costs, thereby influencing the 2015 NICE Dementia Guidelines.