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Southall and Brent Revisited (SABRE)

About the cohort

Start date: 1988
Age at recruitment: 40-69
Sample size at recruitment: 4,858
Estimated current sample size: 2,572

The Southall And Brent REvisited Study (SABRE) is the largest tri-ethnic population-based cohort in the UK, involving nearly 5000 European, Indian Asian and African Caribbean men and women. It investigates the causes of diabetes and disorders of the heart and circulation.

The participants were aged 40-69 when first studied between 1989 and 1991. In 2008 – 2011 a comprehensive combined morbidity and mortality follow up was carried out, together with non-invasive clinical measurements in order to quantify sub-clinical disease. SABRE visit 2 tested hypotheses generated from the Southall and Brent baseline studies and ongoing mortality follow-up.

SABRE Visit 3 (25 year follow-up visit) started in July 2014 and will collect data on participants and their partners. The aims of the study are to build on what has been learned from the first study. Changes in the health of the heart and circulation will be measured, with a special focus on the health of the blood vessels of the brain, as well as early signs of diabetes.   The study will also look at physical function and how well (or otherwise) people  are keeping as they get older

SABRE is part of the Dementias Platform UK (DPUK), a multi-million pound public-private partnership to accelerate progress in dementias research.  

Core funders

  • Wellcome Trust
  • British Heart Foundation 


Website: http://www.sabrestudy.org

Principal Investigator: Professor Nish Chaturvedi


Email: sabre@ucl.ac.uk

Tel: +44 20 7679 9471

Page last updated: 13 Mar 2015


  • Sample size: 0-4,999
  • Age: 40 to 59, 60 to 100
  • Anthropometric: Height, Weight, Waist circumference, Hip circumference, Blood pressure
  • Physical: Cardiovascular, Respiratory, Musculoskeletal, Hearing and vision, Reproductive
  • Psychological: Mental health, Cognitive function
  • Lifestyle: Smoking, Physical activity, Dietary habits, Alcohol
  • Socio-economic: Occupation, Family circumstances, Housing, Education, Ethnic group, Marital status, Social support
  • Biological samples: Blood, Urine, Saliva