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Our successes

Stratified Medicine

The MRC is committed to improving human health through research. By transforming the ecosystem for health research and innovation through pioneering partnerships and capacity-building schemes, the MRC has created valuable platforms, tools, and training programmes. The areas of investment vital for transforming health research include:

Stratified medicine: targeting the right treatment for the right patient at the right time

The transforming health research topics reflect the MRC’s strategic assessment of the opportunity to develop the necessary skills and technology in these areas of focus. The MRC’s commitment to funding the breadth and depth of biomedical research is continued within this sub-set of topics. The following case studies and quantitative data demonstrate the impact of the MRC’s investment into these areas for transforming health research.

Case studies

Smarter trials speed up patients’ access to effective treatments

Adaptive clinical trials are transforming the efficiency of drug development and the MRC has played a crucial role in implementing this innovative method into the UK clinical trials landscape. This trial methodology helps to deliver the right treatment to the right patient faster than ever before. As treatments increasingly become more personalised, accommodating a complex approach within a clinical trial setting requires a new type of clinical trial with a flexible design.

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MRC initiative is instrumental in getting new drug for rare liver disease approved

Scientists from the UK-PBC, a MRC Stratified Medicine Initiative, have been instrumental in getting the first new drug in 20 years for a progressive liver disease approved. Obeticholic acid, to treat primary biliary cholangitis (PBC) received FDA approval in 2016 and NICE approval in March 2017.

Read more about this case study