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What is stratified medicine?

Stratified medicine is based on identifying subgroups of patients with distinct mechanisms of disease, or particular responses to treatments. Stratified medicine allows us to identify and develop treatments that are effective for particular groups of patients. Ultimately, stratified medicine will ensure that the right patient gets the right treatment at the right time.

Understanding the mechanisms underpinning disease is of vital importance in achieving the MRC’s ambition of leading science for better health. As our knowledge of the structural, functional, and chemical abnormalities that occur inside cells and tissues improves, it becomes clear that diseases are essentially sub-groups of these various abnormalities. A stratified approach helps develop a deeper mechanistic understanding of these sub-groups, which can lead to the identification of novel targets and treatment strategies.