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Joint Global Health Trials

Launched in 2010, the Global Health Trials (JGHT) scheme provides funding for research to generate new knowledge about interventions that will contribute to the improvement of health in low- and middle-income countries and is jointly funded by the Department for International Development (DFID), the MRC, the National Institute for Health Research (NIHR) and Wellcome. The partner agencies share the view that in order to have maximum impact on health we need to work together to provide evidence of the best, and most appropriate interventions.

The purpose of this scheme is to fund rigorous research to produce implementable evidence addressing questions of major importance to mortality and morbidity in low- and middle-income countries.  The scheme primarily funds RCTs, but innovative trial methodologies and adaptive designs are also welcome. The scheme focuses on late-stage (equivalent to phase III/IV) clinical and health intervention trials that evaluate efficacy and effectiveness but we may also consider phase IIb stage trials if they are of major relevance to the objectives of the call.

The scheme is open to proposals for any major health related problem affecting low- and middle-income countries, particularly those that affect the most vulnerable populations.  Although the breadth of the scheme is deliberately wide, we particularly welcome proposals for research into chronic non-communicable diseases, including mental health reproductive, maternal and new born health.

The joint funders have run nine successful calls for this scheme and have secured funding for the current 10th call and a further call due to launch in Summer 2020. Applications can be submitted from both UK- and LMIC-led research teams.

Open funding opportunities

Joint Global Health Trials scheme - call 10

Previous joint global health trials calls

Joint Global Health Trials scheme - call 4

Joint Global Health Trials scheme – call 5

Joint Global Health Trials scheme – call 6

Joint Global Health Trials scheme – call 7

Joint Global Health Trials scheme - call 8

Joint Global Health Trials scheme - call 9


All initial enquiries should be directed to the Medical Research Council: JGHT@mrc.ukri.org