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British Regional Heart Study (BRHS)

About the cohort

Start date: 1978-80
Age at recruitment: 40-59
Sample size at recruitment: 7,735
Estimated current sample size: 3,054

The British Regional Heart Study (BRHS) is a prospective study in middle-aged men drawn from general practices in 24 British towns, 7,735 men were recruited in 1978-1980. It was set up to determine the factors responsible for the considerable variation in coronary heart disease, hypertension and stroke in Great Britain. It also seeks to determine the causes of these conditions in order to provide a rational basis for recommendations towards their prevention.

Following the collection of baseline date in 1978-80 the cohort has been followed up through the participants, two-yearly GP Record Reviews, and the Office of Population and Census Surveys. Participants have been re-contacted through questionnaires or assessment in 1983-85, 1992, 1996, 1998-2000, 2003, 2005, 2007 and 2010-2014.

Core funders

  • British Heart Foundation


Website: http://www.ucl.ac.uk/pcph/research/brhs

Principal Investigator: Professor Peter Whincup, Professor Goya Wannamethee, Professor Richard Morris


BRHS Data Sharing: 

Email: Lucy Lennon l.lennon@ucl.ac.uk



Page last updated: 25 Feb 2015


  • Gender: Male
  • Sample size: 5,000-9,999
  • Age: 40 to 59, 60 to 100
  • Anthropometric: Height, Weight, Waist circumference, Hip circumference, Blood pressure
  • Physical: Cardiovascular, Respiratory, Musculoskeletal, Hearing and vision
  • Psychological: Mental health, Cognitive function
  • Lifestyle: Smoking, Physical activity, Dietary habits, Alcohol
  • Socio-economic: Occupation, Finances, Family circumstances, Housing, Education, Ethnic group, Marital status, Social support
  • Biological samples: Blood, Urine