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Cognitive Function and Ageing Studies I (CFAS I)

About the cohort

Start date: 1989
Age at recruitment: >65
Sample size at recruitment: 18,500
Estimated current sample size: 150

The CFAS I study started in the late 1980s with the initial aim of investigating dementia and cognitive decline in a representative sample of more than 18,000 people aged over 65 years. To date there have been in the region of 47,000 interviews with participants in the study. The range of information collected has also allowed the study to investigate depression and physical disability in the older population and also look at healthy active life expectancy. Following baseline interviews, subsets of the cohort have been contacted for 1, 2, 6 and 8 year follow up and the whole sample were contacted for a 10 year follow up. There have also been 500 donations of participant’s brains after death.

CFAS I is part of the Dementias Platform UK (DPUK), a multi-million pound public-private partnership to accelerate progress in dementias research

Core funders

Medical Research Council



Principal Investigator: Professor Carol Brayne


Institute of Public Health
Forvie Site
University of Cambridge School of Clinical Medicine
Cambridge Biomedical Campus


Tel: 01223 330312

Page last updated: 4 Mar 2015


  • Gender: Male, Female
  • Sample size: 10,000-19,999
  • Age: 60 to 100
  • Physical: Cardiovascular, Respiratory, Hearing and vision
  • Psychological: Mental health, Cognitive function
  • Lifestyle: Smoking, Physical activity, Alcohol
  • Socio-economic: Occupation, Family circumstances, Housing, Education, Ethnic group, Marital status, Social support
  • Biological samples: Blood, Other