Research

Genomics England

Supported through the Department of Health, Genomics England is the main pillar of the Government’s strategy to sequence 100,000 human genomes, deliver genomic medicine to the NHS and enhance UK research in genomics.

MRC investment in Genomics England

The MRC provided substantial co-funding to establish the Genomics England Data Centre. Through partnerships with the Devolved Governments of Scotland, Wales and Northern Ireland the MRC has also supported national ambitions in genomic sequencing and medicine with collaborative links to Genomics England to build a UK-wide partnership, asset and capability.

MRC research and Genomics England

The MRC welcomes applications for funding from eligible UK researchers seeking to utilise the 100,000 Genomes Project data and facilities. Applications can come through any of our standard response-mode schemes or relevant targeted initiatives. Researchers will need prior approval by Genomics England to access their assets – please visit the Genomics England website for further information.  Applicants should refer to the MRC’s guidance on the information on specific issues to address within their application.

Applications seeking to use the data, tools and facilities of Genomics England

The MRC is keen to receive applications for funding from eligible UK researchers seeking to utilise the 100,000 Genomes Project data, tools and facilities. Applications can come through any of our standard response-mode schemes or relevant targeted initiatives. Researchers will need to be members of the Genomics England Clinical Interpretation Partnership (GeCIP) to access the dataset and associated tools – please refer to the Genomics England website for further information.  

Applications submitted to the MRC will need to provide assurance in a number of key areas:

  1. A letter from the host institution (Head of Department or equivalent) confirming that they have completed the GeCIP Participation Agreement, including subscribing to the Genomics England Intellectual Property Policy;
  2. A letter from the Principal Applicant that confirms that they are a member of a GeCIP and their research application has been formally approved by the Genomics England Access Review Committee and identifies which Intellectual Property Scenario has been agreed. The MRC is willing to consider an application where these matters are under consideration but the applicant should provide the timing for an expected decision. An MRC award will not be allowed to proceed unless these agreements have been finalised.

As part of the scientific case for support in the application, the applicants will need to confirm that the data available through Genomics England (and elsewhere) is sufficient to fully deliver the scientific objectives, including appropriately powered findings. If the full data is not available at the time of writing the application, then the applicant must confirm when it will be available within the time-frame of work.